The formation of silk fibres in both spiders and silkworms is characterized by a controlled conversion of short range ordered structures in solution into long range ordered beta-sheet rich structures in the final fibre (1). The dynamics of the water and proteins chains involved in the conversion remains, however, unknown. It has been hypothesized that the key controlling phenomenon is a selective amide hydration by water molecules (2). We previously investigated the role of hydration and concluded that water could either promote or inhibit transitions that are involved in silk spinning. Now, we wish to test the structural and dynamics events leading to conformational changes. The expected results will highlight how length and time scales play a role in the control of silk proteins storage and spinning.