In the mono-alcohols (ROH) there is a competition between the packing requirements of the R-group and the demand for the hydroxyl groups to be sufficiently close for hydrogen bonding to occur. The adopted packing motifs can be chains, or catemers, if the R-group is sufficiently small. For bulkier R-groups the molecules may no longer form hydrogen bonded catemers but cyclic dimer, trimer, tetramer or hexamer rings can be created. We have been studying a series of ROH systems at pressure and we have recently found a previously unobserved structure of 2,2,2-trifluoro-ethanol where the R-groups are small enough to allow catemer formation. The neighbouring catemers have a bridging O…O contact of 2.899 Å which is comparable to the 2.760 Å distance between the oxygen atoms involved in the hydrogen bonds. It can be envisaged that a cross-linking hydrogen bond could be formed at higher pressure.