PNIPAM is a thermoresponsive microgel which is interesting due to its lower critical solution temperature (LCST) which is located close to the temperature of the human body. There, PNIPAM undergoes a coil-to-globule transition which is connected to a dramatic change of volume. It is possible to deswell the particles applying pressure. However, the influence of pressure on the coil-to-globule transition and especially the kinetics of the pressure-induced structural changes have not been studied systematically so far. By performing DLS studies as a function of temperature and pressure we found that the LCST increases by approximately 2 K applying a pressure of 300 bar. In preliminary SANS measurements performed at the D22 we were able to confirm these findings. The next step would be the investigation of the kinetics of the swelling and deswelling behaviour upon a change of hydrostatic pressure. In order to conduct such kinetic studies we propose to perform time-resolved SANS measurements using our newly designed stroboscopic high pressure SANS-cell, which provides adjustable pressure cycles. Thereby the pressure can be varied between 1-300 bar with a maximum frequency of 10 Hz.