Antimicrobial drug resistance is an increasing problem worldwide. The prospect of exploiting dendritic structures as scaffolds for antimicrobial peptide (AMP) based agents with increased activity have led to the synthesis of novel AMP dendrimers. Extensive studies on a dendrimer of this type revealed a significant interaction with fluid membranes. They showed that the dendrimers were able to penetrate the lipid bilayer and form lipid-dendrimer micellar-like complexes resulting in solubilisation of mammalian membranes. The dendrimer (BAIN) selected for the present studies has shown high activity towards bacteria of different genera including multi resistant laboratory strains. Importantly, this compound is non-toxic to human cells. We wish to study the interaction between dendrimer BAIN and supported lipid membranes of mammalian and bacterial lipids in order to clarify this selectivity.