The International Continental Scientific Drilling Program (ICDP) performed a dual-phase scientific drilling project to investigate mountain-building processes called Collisional Orogeny in the Scandinavian Caledonides (COSC). The borehole COSC-1 was drilled through the Lower Seve Nappe, as the first of two 2.5 km deep drill holes close to Åre, central Sweden. The recovered rocks comprise a 1650 m thick suite of high grade gneisses and amphibolites with clear Seve Nappe affinities, while the lower 850 m comprise rather homogenous mylonitic gneisses with interfingered K-rich phyllonite bands of cm to several m size and some intercalated amphibolites. The different lithologies all crosscut the core in a subhorizontal direction with foliation of gneisses and phyllonites in the same direction. Albite and garnet porphyroblasts with pressure shadows show syn-deformational growth and the same sub-horizontal alignment. The focus of this study was to detect chemical and mineralogical differences in mylonitic and host rocks and to relate these differences to either metasomatism and deformation or inherited source rock variance. Another goal of this work is to compare chemical core scanning instruments. For this purpose two different X-Ray Fluorescence (XRF) techniques, Laser Induced Breakdown Spectroscopy (LIBS) and hyperspectral imaging served to measure seven samples from the lower 850 m of the COSC-1 core. This data publication comprises the datasets gained in the course of this study. The metadata (OF WHAT?) will be presented in an additional file including XRF data from the Avaatech XRF core scanner in a txt.file as well as datasets of the other used devices in original file formats.