Simulations have demonstrated that mimicking the metal-oxide interface in porous media produces significant variations in the solvents structure over the metal and the oxide for water and isopropanol. In the latter a near complete absence of any molecules over the metal patch is observed. We propose to examine whether the structure proposed by the model simulation can be verified experimentally using supported metal particles on silica. Neutron diffraction will be used to investigate and compare the structure of isopropanol and water in the pores of MCM-41 containing 0.5 nm Ni particles which are uniform in diameter such that approximately 10-15% of the confined fluid will be subjected to structural perturbation from the metal particles. In each case, the structure of water and isopropanol in pure MCM-41 will be compared with that obtained on the supported metal nanoparticles.