There is a huge interest in the properties of water under extreme conditions of temperature, pressure and environment. This interest ranges from the water vapour jets that emanate from the surface of Europa and Encedalus, fuelling speculation for the existence of vast liquid oceans beneath the icy exterior of these moons of Jupiter and Saturn. Somewhat closer to Earth, ice is found in the polar regions of Mars, and there is growing evidence for flows of salty water during the Martian summer, the salt allowing the water to stay liquid at the sub-zero temperatures that are found there. In this proposal we hope to gain insight into the association of a simple biological building block, the amino acid glycine, in extreme conditions relevant for both terrestrial and non-terrestrial environments. This will provide new insight into biomolecular assembly and the natural limits of life.