The seawater parameters oceanic pH and temperature were modified to near future projections for the western Antarctic Peninsula in microcosm experiments. Experiments included two crustose algae, the calcified coralline alga Clathromorphum obtectulum and the fleshy encrusting rhodophyte Hildenbrandia sp., and were run for six weeks. Treatments reflected near future ocean conditions under climate change predictions: increased temperature (3.5 °C × pH 8.1), increased pCO2 (1.5 °C × pH 7.8), combined factors (3.5 °C × pH 7.8), and ambient conditions (1.5 °C × pH 8.1). The physiological responses of the algae were evaluated through photosynthetic parameters (slope to saturation of photo centers (α), saturating irradiance (Ek), maximum electron transport rate (ETRmax), maximum quantum yield of photosystem II (Fv/Fm)), growth, chlorophyll a concentration, and for C. obtectulum calcium carbonate content and Mg/Ca ratio. This dataset is included in the OA-ICC data compilation maintained in the framework of the IAEA Ocean Acidification International Coordination Centre (see https://oa-icc.ipsl.fr). Original data were downloaded from U.S. Antarctic Program (USAP) Data Center (see Source) by the OA-ICC data curator. In order to allow full comparability with other ocean acidification data sets, the R package seacarb (Gattuso et al, 2024) was used to compute a complete and consistent set of carbonate system variables, as described by Nisumaa et al. (2010). In this dataset the original values were archived in addition with the recalculated parameters (see related PI). The date of carbonate chemistry calculation by seacarb is 2024-11-18.