The aim of this study is to try to understand how antimicrobial peptides bind to model lipid monolayers mimicking different cell membrane types. Following our previous work, this study will move into model lipid monolayers containing 2-3 key membrane components. Their combined use helps us to better understand the effects of membrane composition on the amount and location of peptide binding. This constitutes a crucial part of the peptide action mechanisms when disrupting different membranes. The molecular basis of selectivity will in turn help improve the potency of these peptides whilst keeping the toxicity at the minimum.