In Antarctica, solid earth deformation can be attributed to various processes, such as surface load variations mainly caused by present-day (elastic deformation) and past ice-mass changes (glacial isostatic adjustment) or tectonic processes. Several studies have already used geodetic GPS to derive bedrock motion in Antarctica, but they were limited to specific regions or time periods. The GIANT-REGAIN project (Geodynamics In ANTarctica based on REprocessing GNSS dAta Initiative) aimed to reprocess all available GNSS data in Antarctica from 1995 to 2021 consistently. This dataset presents the results of the reprocessing effort. The observational GPS data were processed individually by four processing centers: TU Dresden (TUD), Ohio State University (OSU), Newcastle University (NEWC), and University of Tasmania (UTAS), utilizing different geodetic GNSS software and analysis strategies. The coordinate time series were then combined to form a final time series for each GPS station. Accurate station information are essential for processing GPS coordinate time series with the highest precision and for making the time series geodynamically interpretable. Therefore, all relevant station information has been revised and validated, and the standardized IGS (International GNSS Service) log files are provided. External geodynamic or anthropogenic events can influence the coordinate time series. A list of events (e.g. nearby earth quakes) potentially influencing the coordinate trajectory is provided. Geodetic GPS time series processing involves estimating tropospheric parameters in the form of zenith tropospheric/total delay (ZTD). The time series of ZTD from the individual processings of NEWC, OSU, TUD and UTAS with subdaily resolution are provided.