We propose to determine the possibility for H-addition occurring in the natural anti-oxidants lycopene, melatonin and Delta9-THC, by ALC-muSR on the HiFi instrument. Our theoretical analyses of lycopene models shows only few geometries to be stable, surprisingly including some of the cis-isomers. It is predicted that Mu-addition sites will be likewise limited by conformational and electronic restrictions, effectively rendering many sites unfavourable. Similar arguments are applied to melatonin, and delta9-THC. Objectives include: (1)Determining if H-addition is operative in the natural anti-oxidants lycopene, melatonin, and delta9-THC; (2)Determining relative probabilities of H-addition and H-abstraction from these systems; (3)Establishing theory-design of muSR experiments for anti-oxidants.