This data set contains the post-processed current profiles collected by means of a vessel-mounted ADCP (on the Belgia vessel RV BELGICA) in the Western Mediterranean Sea during May 2022. The TAlPro2022 cruise was part of the Med-SHIP programme. During the whole campaign a VM-ADCP (RDI Ocean Surveyor, 75 KHz) worked along the ship route. The depth range of the current profiler is about 725 m. Data acquisition is carried out using the RDI VMDAS software vers. 1.50.19. The number of bins has been set to 80, with a bin size of 10 m . The instrument ran in narrowband mode and was controlled by computers using the conventional RDI VMDAS software under a MS Windows system with a pinging set to be as fast as possible. No interferences with other used acoustical instruments were observed. The ADCP data have been post-processed with the CODAS3 Software System, which allows extracting data, assigning coordinates, editing and correcting velocity data. Moreover, the data were corrected for errors in the value of sound velocity in water, and misalignment of the instrument with respect to the axis of the ship (about 0.42 degrees). After additional editing, to eliminate suspect values, and those where certain thresholds were surpassed, one netCDF file was created by CODAS3.