These data comprise previously published and additional CTD rosette bottle data including PO₄, Si(OH)₄, NH₃, NO₂, NO₃, δ¹⁸O, δ²H, TA and tCO₂ measurements obtained during the NorthGreen2017 cruise from 11 September 2017 to 1 October 2017. The cruises were part of ongoing research into understanding the interaction between water masses and biogeochemistry on the Northeast Greenland shelf. Where necessary (e.g. tCO₂) samples were spiked with HgCl to eliminate biological changes in the sample. Samples were stored in the dark until analysed.