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Interactions of native vs. modified protamines with Gram-negative model biome...
Protamines are cationic antimicrobial peptides found commonly in the sperm cells of fish such as herring and salmon that are particularly active against food-borne Gram-negative... -
Using neutron reflectivity from monolayer models of bacterial cell membranes ...
Antimicrobial peptides are being investigated as an alternative to antibiotics, as bacteria seem less able to acquire resistance to them. We have been investigating the way in... -
Interaction of deuterated thermo-responsive nanogels with lipid multilayers
Small gel molecules which can change their properties in response to, for example temperature are important for applications such as drug delivery through the skin. In order to... -
Incorporation of PAN-pyrene swollen micelles in crosslinked polyelectrolyte f...
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the micelles... -
Realistic bacterial membrane mimetics to understand antimicrobial activity & ...
We will use neutron reflectivity measurements of lipopolysaccharide (LPS) layers at the air-water interface to help develop a realistic mimetic for the periphery of bacteria... -
Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Ca-ions at PS-containing biomimetic lipid layers: Interfacial water
Lipid membranes provide a sensitive platform for a variety of biological functions, and membrane lipid distributions are carefully regulated. In this project we plan to study...
