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Studying the lateral organisation of mixed phospholipid bilayers by diffuse n...
Off-specular neutron reflection is potentially a powerful technique for studying the lateral organisation of phospholipid bilayers. However, this has not yet been demonstrated.... -
Which is it? ¿ Neutrons distinguish monolayers xrays can¿t.
We have obtained the monolayer structure diffraction patterns from several iodoalkanes adsorbed on graphite, of interest in the study of non-covalent bonding. However, it is... -
Copy of: Neutron Diffraction study of the monolayer structures of cyclohexane...
Following a recently succesfull measurement of the structure of a monolayer of n-butane adsorbed on MgO we wish to perform neutron diffraction measurements of monolayers of... -
Nanophase separation in monolayers of stratum corneum mixtures
There is considerable effort being put into the modelling of the outer layer of skin, the stratum corneum, because of impending EU restrictions on the use of animal skin for... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
The calcuim mediation interaction of DNA with monolayers of DSPC and DOPE
The main objective of the present work is to complete some work aimed at gaining an understanding of the interaction of phospholipid membranes containing the neutral helper... -
Amide monolayers at the polymer melt air interface
This proposal seeks to identify and characterise the adsorption of primary linear amides that adsorb to the surface from the bulk of a polymer melt. These layers are... -
Protein density profile near protein-resistant self-assembled monolayers: Sen...
Oligo(ethylene glycol) self-assembled monolayers (SAMs) effectively prevent the adsorption of proteins from biological media. Despite the importance of this effect for... -
Neutron reflection from nanoparticles interacting with insoluble monolayers
Cell-nanoparticle interactions are complex, involving several specific and non-specific intermolecular forces between a wide range of particulate and molecular species . There... -
Effect of method of preparation on the composition of complex monolayers
In the present proposal neutron reflectivity will be used in combination with contrast variation to detect changes in the presence (and size) of microdomains in monolayer films... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
Neutron reflectivity studies of the interaction of amphotericin with phosphol...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Surface structure of monolayers formed by novel di- and tri-chain cationic li...
The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with... -
Structure of phospholipid monolayers containing lipid-PEG-ligand
The incorporation of lipid-PEG-ligand molecules into liposome membrane imparts targeting ability and specificity to liposomes. Crucial for the targeting ability is the... -
Adsorption of tetraalkylammonium (R4N+) counterions into monolayers of surfac...
This proposal is to explore adsorption of tetraalkylammonium (R4N+) counterions into monolayers of surfactant anions (see Figure 1) at the air-water interface, as a function of... -
Ozonation of organic films at the air-water interface of atmospheric aerosol
The Earth¿s climate is strongly influenced by atmospheric aerosols. Organic surfactant films on these aerosols influences their size, optical properties and ability to act as...