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Structural examination of self-assembled floating membranes below grafted lip...
Robust, reliable, and protein-free bacterial membrane mimicking systems compatible with the high through put screening techniques will largely facilitate the discovery of new... -
Interaction of an antimicrobial peptide from Lactobacillus gasseri supernatan...
A short peptide, composed of 12 amino acids (EFVFVAHAVPVM), presenting a strongly hydrophobic character, was recently isolated from Lactobacillus gasseri supernatant (AMP12).... -
Interplay of apoptosis regulating Bcl-2 proteins with mitochondrial membranes...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Interfacial adsorption of keratin as characterised by neutron reflection
This proposal constitutes part of our ongoing study towards understanding the adsorption of keratins and their interactions with ionic surfactants at the solid/water interface.... -
Satisfying the need for contrast in antimicrobial research
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Surfactant Modified Salivary Pellicles
Salivary films are (mostly) proteinaceous nm-thick films that form on any type of surface upon exposure to saliva. The role of the pellicle is manifold. Among its functions,... -
Quantifying antibiotic resistance using bacterial model membranes
The Gram negative bacterial outer membrane protects the bacterium from toxins such as antibiotics and is partially responsible for the rapid rise in antibiotic resistance in... -
Introducing the O-antigen in Bacterial Outer Membrane in vitro Models Pt. III...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Ion mediated surfactant adsorption on cellulose films
In recent work with Unilever we have been investigating the structure of gels formed by partially oxidised cellulose nanofibrils for use in sustainable personal care products.... -
Interplay of apoptosis regulating Bcl-2 proteins at mitochondrial membranes u...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). This pathway is a major regulator in cell... -
Defects in the Core Oligosaccharide in Gram Negative Bacterial Outer Membrane...
The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial... -
A new approach to look at membrane in plane organisation via giSANS
Biological membrane in plane organisation is a challenging topic, specially since it has been suggested to depend on curvature. So far the main approach to study curvature... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims at elucidating how bile salts (BS) structure influences their interfacial behaviour and their impact on fat digestion. Neutron reflectivity (NR) is the... -
Satisfying the need for contrast in antimicrobial research
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Lipid exchange between polymer stabilised nanodiscs and biomimetic bilayers a...
Polymer-stabilised lipid nanodiscs are discoidal structures composed on a central core of lipid bilayer encapsulated and stabilised in aqueous solution by amphipathic... -
Structural characterisation of vaccine-adjuvant interactions using neutron re...
This dataset has no description
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A biophysical approach of studying the molecular interactions of a novel anti...
Gram negative (-ve) bacteria possess numerous defenses against antibiotics, not the least of them being the intrinsic permeability barrier afforded by their outer membrane (OM)... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
Antibiotic paths through the bacterial outer membrane: The strange case of va...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is...
