6 datasets found

Definition of functional regulatory regions in the vast non-coding fractions of mammalian genomes remains a daunting challenge that underscores our limited understanding of...

The connection between evolution of regulatory elements and downstream gene expression is incompletely understood in mammals. We carried out a large-scale comparison of matched...

This study determines that genome skimming, shallow depth of sequencing, is capable of accurately quantifying global DNA methylation level across a range of vertebrates.

Mitochondrial heteroplasmy, the presence of more than one mtDNA variant in a cell or individual is not as uncommon as previously thought. It is mostly due to the high mutation...

This study used comparative epigenomic data from multiple mammalian species to investigate the roles of DNA methylation in gene evolution, species trait evolution, and genomic...

Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates