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Next Generation Sequencing Approach to Evaluate HIV Virus in Blood Compartments
Analysis of low frequency HIV-1 drugs resistance mutations and virus distribution in the blood compartments -
Nano-DMS-MaP allows isoform specific RNA structure determination
Genome-wide measurements of RNA structure can be obtained using reagents that react with unpaired bases, leading to adducts that can be identified by mutational profiling on... -
Microbial community structure in the central Arctic Ocean
Bacterial and Archaeal community structure in the central Arctic Ocean -
Broad miscellaneous virus genome sequencing project
This project was created to facilitate virus data submission by the Broad Institute and should be used when the virus being sequenced does not fit into a larger "effort driven"... -
In vivo single-molecule RNA structure analysis reveals COOLAIR RNA structural...
We used the SHAPE reagent, 2 methylnicotinic acid to do the in vivo RNA secondary structure chemical probing. NAI was prepared as reported previously. Briefly, Arabidopsis... -
HIV-1 RNA structure and heterogeneity analysis
The goal of this set of experiments is to determine the structure of HIV-1 NL4-3 and NHG RNA structure using a novel algorithm that allows for the identification of multiple RNA...