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Protein exchange at the solid/liquid interface
The balance of proteins adsorbed at a surface is important in a wide range of situations, e.g. implants, nanoparticles. The accepted model is that rapidly diffusing proteins... -
Membrane reconstitution of human dihydroorotate dehydrogenase using lipid-det...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
The effect of dendrimer surface functionalization on the interaction with mod...
Dendrimers are a unique class of nano-structured vehicles for drug and gene delivery into intracellular targets. Their surface chemistry influences their transport across... -
Investigating the response of lipid bilayers to physically structured substrates
The functionality of biological membranes is closely tied to their structural behavior. To understand this behavior we propose to study the conformality of artificial lipid... -
Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Po...
In this proposal, we request beamtime to study the very unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate potassium and ammonium salt (K(AOT)...