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Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Free Floating Higher Plant Membrane Mimetics
We have engaged in a long term effort to build accurate bio-mimetic systems for complex structural biology studies. Recently, we have found that thiolalkylamidealcohol... -
Defects in the Core Oligosaccharide in Gram Negative Bacterial Outer Membrane...
The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial... -
SANS studies of phospholipid:sterol vesicles and the membrane interactions of...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Effect of oxidative stress on polyunsaturated lipid bilayers modulated by cho...
The exposure of biological membranes to reactive oxygen species is key for many pathological conditions, including inflammation, infection, or sepsis. Lipid peroxidation is... -
SANS studies of mixed phospholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Investigating the structure of the pulmonary lung surfactant at the air-water...
This dataset has no description
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Chloride Intracellular Channel insertion into Tethered Bilayer Membranes
Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer... -
Lipid dynamics in yeast cell membranes effect of ergosterol and its precursors
A cell membrane can contain hundreds of different lipid molecules, but our understanding of the dynamics of cell membranes is very limited. As a result of a collaboration... -
Study of the interaction of thermoresponsive nanogels with model skin
Skin is an important site for drug delivery. However skin, the stratum corneum which is mainly composed of mixture of lipids, cholesterols and fatty provide a barrier for drug... -
Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Adsorption of liquid crystal nanostructured particles to model hydrophilic an...
Cubosomes and hexosomes are particles with internal liquid crystal structures of the bicontinuous cubic or reverse hexagonal nanostructures respectively. The nanostructure... -
Membrane perturbation and permeabilization by the lysosomotropic detergent MSDH
Lysosomes are subcellular organelles with acidic interiors (pH 3.5-5), containing enzymes that break down macromolecules and intracellular waste. Controlled release of lysosomal... -
Neutron reflectivity studies of the interaction of amphotericin with model ce...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Surface structure of monolayers formed by novel di- and tri-chain cationic li...
The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with...
