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Investigation of Folded Globular Maltose Binding Protein Based Hydrogels
We have developed a new model to describe the structural architecture of hydrogels composed of cross-linked maltose binding proteins (MBP), supported by multiple techniques... -
Perfluorocarbon-loaded polymeric nanoparticles with multiple perfluorocarbon ...
Ultrasound is a very attractive and patient-friendly imaging technique, as it is easy to use, fast and non-invasive. Nevertheless, its use is severely limited by the low... -
Bulk interactions of surfactant molecules in aqueous particle suspensions
Surfactants represent an important class of compounds owing to their ability to readily locate at interfaces, be it airliquid, liquidliquid or solidliquid. As such,... -
A SANS study of nano-gels with a temperature tunable bio-interface
Hyaluronic acid (HA) plays a key role in tumour cell bio-adhesion and, as such, this interaction opens up possibilities for targeted tumour pathologies We have created a... -
SANS Investigation into the Mode of Interaction between Antibiotics and Diffe...
In this part of proposed work, we wish to explore how antibiotics minocycline and tetracycline interact with model lipid bilayers in the form of SUVs, mimicking key features of... -
Using SANS2D to resolve the opening of MscL clusters in proteoliposomes in re...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the... -
Architecture of lipid-protein nanoglobules in velvet worm prey capture slime
Fiber fabrication in animals is an important inspiration source for polymeric materials. Velvet worm prey capture slime represents a unique way of fiber fabrication by using... -
Polystyrene latex - 'single crystal' structure studies and melting under flow
For deionised, charge stabilised latices, there has been some uncertainty about the stacking sequence of close packed layers in samples at equilibrium. The ABCA stacking in... -
Radiation induced changes in block copolymer micelles
Block copolymer micelles have been used to encapsulate various chemotherapeutic drugs, which can be delivered to the tumour site using the so-called Enhanced Permeation and... -
Using SANS to understand the structural basis for the rheology of molten choc...
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
Using SANS to understand the structural basis for the rheology of molten choc...
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
pH responsive Core-Shell-Corona (CSC) micellar complexes: Corona- and teleche...
Coacervation is an electrostatically-driven liquid-liquid phase separation process, resulting from the association of oppositely charged macro-ions. In this framework,... -
Controlled release from lipid-alkylglycoside vesicles, as triggered by amylas...
The consumer demands for functional food have increased the interest for encapsulation of bioactive compounds in the food industry. Encapsulation is crucial, since these... -
Interaction of a pH-sensitive Polymer with a Model Lipid Membrane in the Form...
This SANS experiment was proposed by 4 PhD students from 3 different institutions in a Marie-Curie Training Network. They are all in the second year of their PhD and their... -
Investigation of membrane polymer complex using SANS
The interaction between lipid vesicles and macromolecules, like polymers is of intense importance from both theoretical and practical point of view. On one hand lipid vesicles... -
Adsorbtion from nematic mixtures: bulk characterization
The aim is to measure any tendency towards phase separation in a nematic mixture to complement an adsorption study on the same mixture. The base is 4-pentyl 4¿- cyanobiphenyl... -
Bacterial lipoteichoic-acid (LTA) micelles: From molecular self-assembly to m...
Whilst the biological effect of lipoteichoic-acid (LTA) contributing to bacterial infections is widely reported in microbiological and immunological studies, very little is... -
Origin of co-nonsolvency, based on the Flory-Huggins interaction parameters o...
Co-solvency and Co-nonsolvency are two extreme phenomena in the field of polymer solution. The former is the phenomenon that a mixture of two nonsolvent forms a good solvent for... -
On the structure and composition of non-lamellar lipid-based liquid crystalli...
Liquid crystalline particles consisting of glycerol dioleate (GDO) / soy phosphatidylcholine (SPC) mixture and stabilised by polysorbate 80 (P80) have proven to be suitable as... -
Structure and mobility of surfactant additives in PDMS resin
Polysiloxane materials are commonly used in marine coatings due to their inherently low surface energy and flexibility which makes them suitable base materials for foul release...