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Engineering nanoparticles for protein therapeutics - quantifying membrane acc...
The self-assembly properties of lipid systems can be exploited to form lipid membranes with complex morphologies. These include membranes with a lattice-type internal structure... -
Spin dynamics on the frustrated Fe7 molecular cluster
Fe7 is a magnetic cluster formed by two Fe(III) triangles bridged together by a Fe(III) ion. The antiferromagnetic exchange interaction within the two triangles makes the system... -
Solution aggregation of short peptide surfactants
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
Structure determination of solution aggregation of single alkyl chain PC surf...
We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of... -
Magnetic Excitations in YbNiSn
YbNiSn is an Ising ferromagnet with non-colinear spins that undergoes a first order magnetic transition in low magnetic field (0.9 T). The transition is associated with strong... -
Understanding the microstructure of polymer blends used as control release co...
Solid oral dosage forms consist of polymer layer encapsulated drug-bound particles with a desired drug release profile e.g. pulsatile, controlled, delayed and targeted,... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Structural Studies of High Level Waste Glass
The aim of this proposal is to develop a methodology to investigate multicomponent glass structure, combining neutron diffraction, XRD, NMR, ab initio MD, and RMC. We wish to... -
Quantitative analysis of precipitate coarsening in V and V-Mo microalloyed steel
Ever-more stringent environmental regulations have driven the automotive industry to continuously develop lightweight solutions in automotive body sheet materials, without... -
SANS Study of the interaction of reconstituted model wheat waxes with non-ion...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
The effect of interface roughness on proximity induced magnetisation and inte...
Interface effects, including proximity induced magnetisation (PIM), play an import role in many spintronic devices employing heavy metal/ferromagnetic structures. Interface... -
Interaction of polypeptide with surfactant: SANS study of solution aggregation
This proposal constitutes part of our ongoing study towards understanding the solution aggregation of collagen based polypeptides and their interactions with model surfactants.... -
Assessing a potential method to form kinetically trapped, self-assembling nan...
Cyclic peptide-polymer conjugates can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. Recently, using SANS and... -
Solution aggregation of lipopeptides: SANS structure determination
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Effect of alloying on the misfit of Ni-Ni3Al-Ni3V alloys
The exceptional high temperature mechanical properties of Ni-base superalloys has resulted in their widespread use in high temperature applications. These alloys conventionally... -
Study on the cascade de-excitation processes in muonic hydrogen atom
Muonic hydrogen is a bound state of a proton and a negative muon. It is an ideal system to study the bound-state QED effects and atomic scale phenomenon.When a muon stops in... -
Monitoring the structural transition of a hydrophobic amphiphile from the iso...
We propose a SANS experiment to investigate a structural transition involving an alkylated fullerene-C60 (an alkyl-aromatic hydrophobic amphiphile) in alkane solvents from an... -
Probing membrane localisation of molecular rotors (SANS)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Co-surfactancy of oil-soluble and water-soluble surfactants in emulsion stabi...
The structures of emulsions formed from mixed oil-soluble and water-soluble amphiphiles (respectively derivatives of polyisobutylene, PIBSA, and polyacrylamide, PAM) will be... -
A study of hole injection efficiency for a model conjugated bilayer system
Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our...