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Neutron Reflectivity Study on Multi-domain DNA Molecular Motors
DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We... -
Wittig Reaction: Cleaning up 50 years of Waste in Metal-Free Catalysis
Our recent works have solved a 50 yr old problem (in part) with computational steering successfully guiding synthetic work towards a wittig process catalytic in phosphine. The... -
Defects in the Core Oligosaccharide in Gram Negative Bacterial Outer Membrane...
The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial... -
Structure and activity of Membrane Proteins immobilised to solid supports.
Membrane Proteins (MPs) consist of about 1/3 of the proteome but the structural information available is very limited compared to that for soluble proteins. Despite this at... -
Micellar modifiers for CO2
This proposal focuses on a new approach to the formation of rod-like micelles in supercritical CO2 (scCO2). Recent successful high-pressure SANS (HP-SANS) results have shown for... -
Opening up microemulsion phases in CO2
New types of water-in-CO2 microemulsions using mixed surfactant systems will be investigated by high-pressure SANS (HP-SANS). Exciting new results (see report on RB820030) have... -
Chloride Intracellular Channel insertion into Tethered Bilayer Membranes
Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer... -
New CO2-philic surfactants
The proposal aims to explore water-in-CO2 (w/c) microemulsions with new, very promising hydrocarbon surfactants. The compounds are generated using standard chemistry1 but with...
