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Effect of drug on the micelles formed by ionic surfactants
The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles... -
Solubilisation of Drug Molecules in Nonionic Surfactant Micelles: Structural ...
This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the... -
Investigation of pseudo-condensation of supercritical H2 in nanoporous hydrog...
This proposal aims to use small angle neutron scattering for characterization of hydrogen adsorption (including the provision of a quantitative value for the absolute hydrogen... -
SANS studies of phospholipid:sterol vesicles and the membrane interactions of...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Elucidating the unique role of non-standard collagen helices in forming key p...
The collagens are the most abundant proteins in mammalian systems, comprising up to 25% of human proteins. Their three-stranded triple helix structures are a major determinant... -
Evolving microemulsions - tuning selectivity in oxidation reactions
We have begun to explore the synthesis, reactivity and physicochemical properties of a number of surface-active metal complexes, to devise a method for the catalytic... -
Binary colloidal mixtures - SANS contrast variation to study high concentrati...
Mixtures of colloidal particles of essentially two different sizes are commonly used in technological applications such as film formation on surfaces, paper coatings, etc.... -
Structural and mechanistic study of nanocapsule / hydrogel composites for dru...
The targeted delivery of non-water soluble drugs for applications such as cancer remains a major challenge. Nanocapsules are new materials that can act as a depot for such drugs...