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The origins of Biosurfactant self assembly
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
The action of membrane lytic compounds on model membranes.
The study of antifungal and antibacterial action is of great interest and there are still many unknowns concerning the action of membrane lytic materials, and the way that... -
Probing perfume surface delivery / retention rates in-situ
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
Surface structure of ethoxylated PEI/SDS mixtures: optimising surface properties
The strong interaction between polyelectrolytes and ionic surfactants can result in pronounced surface adsorption and the formation of surface multilayer structures. This... -
Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Ca...
In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt... -
How perfume structure affects surface coadsorption with anionic surfactants
In a recent EPSRC / Unilever / Oxford CASE project we have used NR to explore and develop optimised delivery mechanism for active benefit agents such as perfumes. In particular... -
AGGREGATION BEHAVIOUR OF A NOVEL P-AOT SURFACTANT
This proposal aims to provide essential surfactant micellisation structural information of significant interest in its own right but also as key information for our on-going... -
Manipulating surface adsorption of SLES surfactants using temperature
Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Interaction of lignosulphonates with model surfactant systems by neutron refl...
With the biobased economy growing substantially and pressure to reduce reliance on palm and crude oil derived materials, it is vital that the Home and Personal Care industry... -
manipulating surface adsorption usinf ethoxylated polyelectrolytes
The strong interaction between polyelectrolytes and ionic surfactants can result in pronounced surface adsorption and the formation of surface multilayer structures. This... -
SANS Studies on Aggregate Structures of Peptide Amphiphiles
Peptide amphiphiles have special self-assembling behaviors and important aggregate properties, which make them have many potential applications both in vitro and in vivo. The... -
Surface properties of biogenic polyaminesurfactant mixtures
Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and... -
Multilayering of Methyl Ester Sulphonates at the Air-Aqueous Interface
Surfactants usually form a single layer of molecules at the surface of water. We have shown, surprisingly, that under certain conditions more than one layer may form. When this... -
Interactions of Cationic Surfactants with Phospholipid Vesicles: Influence of...
Surfactants are frequently used in personal care products to improve the wetting and oil solubilizing qualities of the products, which also leads to the skin irritation by... -
The effect of bilayer rigidity on the interactions with perfluoroalkyl compounds
Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment.... -
Self-assembly of polymer-stabilised cyclopeptide nanotubes
SANS will be used to determine the structure of nanotube dispersions formed by H-bond stacking of cyclopeptides coated with a sheath of stabilizing polymer. Cyclopeptide... -
Interactions of Surfactant Mixtures with Phospholipid Vesicles: the Influence...
Surfactants have been widely used in cosmetics, detergents and pharmaceutical industries. These applications are always accompanied by surfactant-induced skin irritation which... -
Model anionic/non ionic surfactant adsoption at the interface below room temp...
An experiment performed on INTER last year found extreme non ideal mixing between C12E8/SLES3 at the air water interface: this feature became more extreme as the temperature... -
NR Investigation of Structural Basis Underlying Synergistic Binding of Lipope...
In this part of the proposed work, we wish to explore how antibiotics and antimicrobial peptides interact with model lipid bilayers in the form of a supported lipid bilayer,...