39 datasets found

Whole genome sequencing of bacteria in clinical samples, mainly from the A Coruna University Hospital Complex (CHUAC, Galicia, Spain) and associated collections, under project...

Multi-drug resistant gram negative bacteria (also known as “Superbugs”) are causing infections in vulnerable patients in hospitals around the world. Much of the clinically...

Enterobacteriaceae strains isolated from newborns in a Chinese hospital

Hospital wastewater is an increasingly recognized reservoir for resistant Gram-negative organisms. Factors involved in establishment and persistence of Klebsiella pneumoniae...

Infections with antimicrobial resistant organisms are an important cause of morbidity and mortality worldwide and an ever-growing public health concern. The ability of tracking...

A collection of Gammaproteobacteria isolated from environmental and patient sources originating from a single hospital in the United States

The goal of this project is to identify carbapenemases and other beta-lactamases in clinical isolates with WGS and assess their mobilization potential . The results can support...

Cell-free expression systems enable rapid prototyping of genetic programs in vitro. However, current throughput of cell-free measurements is often limited by the use of...

Prospective collection and sequencing of positive blood culture isolates in hospitalized adults in Cambodia

Here we present a comprehensive collection of 737 whole-genome sequenced bacterial isolates from humans to understand the blueprint of human gastrointestinal microbiota. This...

Carbapenem Resistant Enterobacteriaceae strains including Klebsiella, Escherichia, Enterobacter, Citrobacter and Pantoea species isolated from patients and hospital environment.

The level of antibiotic resistance in neonatal infections and its impact on mortality in low-middle income countries (LMICs) is unacceptably high. The study, entitled the Burden...

We have developed a bladder-specific bacterial reference database consisting of 1134 genomes to aid in genomic, functional, and experimental analyses of the human bladder...

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Bloodstream infection is a major cause of morbidity and mortality worldwide. Early pathogen detection and administration of appropriate antimicrobial therapy substantially...

The Genome sequencing and assembly of Klebsiella spp.

Whole genome sequencing of bacterial pathogens is combined with machine learning and data mining of the electronic medical record to enhance outbreak detection in hospitals and...

This project aims to develop DNA and RNA sequencing as tools for pathogen discovery in a clinical setting.

Isolation of pathogens directly from primary liquid blood culture infection diagnosis using WGS