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Differential gene expression analysis for symbiotic hydras acquired by horizo...
Hydra vulgaris is a fresh water cnidarian and is able to bear green algae Chlorococcum in the endodermal cells. We compared gene expression between nonsymbiotic polyps and... -
Gene expressions in the three Hydra stem cell populations
Transgenics Hydra expressing eGFP in interstitial stem-cells (ISC), gastrodermal epithelial cells (gESC) or epidermal epithelial cells (eESC) were used to sort these populations... -
Hydra vulgaris strain:Ind-Pune Epigenomics
Epigenome landscape of Hydra and its dynamics during body axis patterning. -
Hydra transcriptome analysis
The main goal of the study is to produce a reference transcriptome for the cnidarian polyp Hydra vulgaris, which will be used for later quantification studies. Both Illumina and... -
RNA-seq Time Course of Developing Hydra Spheroids in Hydra Medium (HM) and is...
Probing the role of mechanical oscillations in Hydra regeneration by manipulating environmental osmotic properties. Single spheroids from a period of 22h were collected at 1h... -
The role of DNA methylation in genome defence in Cnidaria and other invertebr...
Considerable attention has recently been focussed on the potential involvement of DNA methylation in regulating gene expression in cnidarians. Much of this work has been centred... -
Genome-wide maps RNA Polymerase II and Histone H3 of Hydra vulgaris
Hydra have a remarkable ability to regenerate after bisection or dissociation. Thus, Hydra is a unique model for studying the mechanisms underlying stemness and self renewal... -
Gene expression profiling in the basal metazoan Hydra vulgaris (strain AEP)
This study aims to determine the molecular signatures/fingerprints for the three stem cell lineages (ectodermal- and endodermal epithelial cells, interstitial cells) in the... -
Single cell analysis reveals the molecular signaling and cellular composition...
We use single cell RNA-seq from a regeneration time course to identify the molecular and cellular features of Hydra head regeneration Overall design: We bisected Hydra and... -
Extracellular vesicles mediate molecular signalling during Hydra regeneration
Recent body of evidence demonstrates that extracellular vesicles (EVs) represent the first language of cell-cell communication emerged during evolution. In aquatic environments,... -
Tracking the origin and evolutionary dynamics of RNA editing in metazoans
Whole-genome DNA-seq and strand-specific RNA-seq on 18 species, including 14 metazoans and four unicellular eukaryotes closely related to metazoans. For each species, two to... -
The transcription factor Zic4 promotes tentacle formation and prevents epithe...
Purpose: The mechanisms driving epithelial cell fate decisions to create differentiated body structures (such as tentacles and basal disk) are not understood in Hydra. We... -
Oral Regeneration Is the Default Pathway Triggered by Injury in Hydra
Animals capable of whole-body regeneration can fully restore any tissue lost due to injury. Because different types of injury may require the regeneration of different... -
Microbiome Raw sequence reads
Maintaining epithelial integrity and a well-orchestrated host-microbiome crosstalk is essential for organismal health and life span throughout the animal tree of life. In human... -
Stem cell differentiation trajectories in Hydra resolved at single cell resol...
The adult Hydra polyp continuously renews all of its cells using three separate stem cell populations but the genetic pathways enabling these dynamic tissue properties are not... -
The effect of Feeding on Hydra
The effect of feeding on Hydra vulgaris AEP was investigated at various time points post-feeding: 4 hours, 12 hours, 24 hours, and 120 hours. Our goal was to identify... -
RNA-seq of Hydra body segments and regenerated Hydra animals
Positional RNA-sequencing of isolated Hydra body pieces and RNA-sequencing of fully regenerated Hydra animal was combined with RNA-sequencing of actively regenerating spheroids... -
Hydra single-cell RNA-sequencing
Pacemaker neurons exert control over neuronal circuit function by their intrinsic ability to generate rhythmic bursts of action potential. Recent work has identified rhythmic... -
Integrative analysis of Hydra head regeneration reveals activation of distal ...
The cnidarian model organism Hydra has long been studied for its remarkable ability to regenerate its head, which is controlled by a head organizer located near the hypostome.... -
H4K20me1 plays a dual role in transcriptional regulation during regeneration ...
The evolution of the first body axis in the animal kingdom and an extensive ability to regenerate makes Hydra, a Cnidarian, an excellent model system to understand the...