238 datasets found

Anopheline mosquitoes transmit Plasmodium parasites to humans, and are responsible for an estimated 219 million cases of malaria, leading to over 400,000 deaths annually. The...

Genome sequencing of male and female Anopheles gambiae.

Anopheles gambiae is a malaria vector. The mosquitoes have evolved an innate immune system through the interactions with various commensal and/or pathogenic microbes the...

The study is bioprospecting for novel anti-mosquito blends or compounds that show promise in integrated vector management of malaria vectors. Efficient locally accessible...

Transcriptome sequencing of arthropod cell lines

Transcriptome sequencing of arthropod cell lines

Illumina WGS of DNA derived from single mosquitoes to identify polymorphisms relative to published reference.

Museum collections contain enormous quantities of insect specimens collected over the past century, covering a period of increased and varied insecticide usage. These historic...

To examine the effects of 20E treatment on mosquito gene expression, treated mosquito cells were examined by RNA-seq to determine the influence of 20E treatment. Overall design:...

The heavy use of pesticides in intensive agricultural areas often leads to the contamination of neighbouring mosquito larvae breeding sites. Such exposure to complex...

Transcriptome sequencing of arthropod cell lines

Here we develop precision guided Sterile Insect Technique (pgSIT) in the mosquito Anopheles gambiae to generate an inducible male-sterilizing and female-eliminating system for...

Differences between males and females are central to the biology of thousands of species across the tree of life. Sex chromosomes play a key role, but despite their their...

Malaria control relies on insecticides targeting the mosquito vector, but is being increasingly compromised by insecticide resistance. Elevated expression of metabolic enzymes...

We custom-built a bioinformatics pipeline to search for 20E-modifying enzymes in the accessory glands of Anopheles gambiae males, searching for ecdysteroid kinases (EcK),...

For insecticides acting via direct contact it is generally accepted that the insecticide penetrates the insect’s leg integument and enters the insect’s circulatory system from...

Transcriptome sequencing of arthropod cell lines

We provide a broad overview of sequence diversity in An. gambiae mature microRNAs, including annotation of novel microRNAs identified in this study. Overall design: Non-coding...

Transcriptome sequencing of arthropod cell lines

We present population genomic analyses of 111 specimens sampled from west to east Africa, including the first whole genome sequences from oceanic islands, the Comoros....