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Microemulsion formulations for local anaesthesia
Although microemulsions have been investigated as potential drug delivery vehicles, little work has been performed establishing the detailed molecular architecture of the... -
Multi-catalyst ensembles - aggregation structure and selectivity
There is exciting potential for SANS to resolve an important problem in homogeneous catalyst chemistry. The Pd-chiral catalyst 1+ below has significant pan-industrial potential... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Magnetic phase diagram of supermagnetic nanostructures in Fe-Ag thin films.
Nanogranular thin films of FexAg100-x (x=7,15,35) are an excellent system to study the interplay between the nanostructure and the magnetic behaviour, which is triggered by the... -
Detailed structures of surfactant micelles
Measurements are required for Sans2d resolution checks and also the overlap of the two Sans2d detectors. Proposal submitted to panel and they deemed it should be done as... -
Employing Rheo-SANS to understand how silk is spun
Combining structural information about silk proteins in solution whilst undergoing mechanical shear will open a new window into silk production in vivo and provide valuable... -
Examining the Structural Changes of a Central Nervous System Neurotransmitter...
GluR0 is a glutamate sensitive potassium ion channel from the cyanobacterium Synechocystis which has been identified via primary structural sequencing to be similar to... -
Building a model for gastric mucins
Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection.... -
Time of Flight MISANS
MISANS is the combination of Modulation of Intensity Emerging from Zero Effort (MIEZE) and Small Angle Neutron Scattering (SANS). SANS is used to determine the microscopic... -
Silk fibrillogenesis: Morphology, structure and hydration of the intermediate...
At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of... -
Biotemplated hydroxyapatite for radionuclide remediation
Abstract: Apatites (general formula Ca5(PO4)3(OH,F,Cl)) are suitable materials for nuclear waste remediation and storage because they can incorporate actinides in their... -
Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an...