-
Understanding the Affect of Lipid Tail Saturation on Anaesthetic Interaction ...
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Lipid mesophase alignment induced by nanoparticles: Mesophase determination a...
At a recent experiment at the ILL using D22, we made an incidental observation that addition of hydrophilic silica (SiO2) nanoparticles (NP; D~14 nm) induced alignment in the... -
Neutron Reflectivity study of lipopolysaccharide complexes with lateral domai...
We propose to investigate the role of lateral phase separation on LPS insertion into model membranes and the effects of target membrane structure and composition. A comparison... -
Floating Bilayers Deposited on Au / Fe Surfaces
There is currly great interest in the use of neutron reflection to study model bilayers. We have produced a model membrane system that is strongly associated with the substrate,... -
Understanding Phospho-L-Serine (PS) role in the Organization of Cholesterol C...
Our goal is to understand the role of POPS, a lipid component only found in the inner leaflet of plasma membrane, in the organization of cholesterol in cell membranes. Our... -
Is cloud water nitrate radical chemistry important in oxidising thin films on...
Projected climate change is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and reflectivity, important climatic effects.... -
Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Probing membrane localisation of molecular rotors (SANS)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Using Magnetic Contrasts to Establish the Mechanism and Kinetics of Lipid Fli...
In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied...