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Relation between surface tension and adsorbed amount of proteins at the air/w...
The surface tension of proteins often exhibits a reproducible lagtime, which is sensitiv to a range of conditions such as concentration, pH, ionic strength. We have also found... -
DPPC bilayer oxidation by aqueous singlet oxygen
Oxidation of membrane lipids by Reactive Oxygen Species, ROS, in cells may impact ageing, cell apoptosis and cancer. We propose to use our skills obtained studying the oxidation... -
Interfacial Structure of Colloidal Dispersions - the air/latex interface
Adsorption of colloidal particles to an interface is of fundamental interest in understanding wetting, capillarity and colloidal forces as well as being of practical importance... -
The Interaction of wild-type and mutant Puroindoline B with Model Bacterial M...
Bacterial and fungal infections of cereal crops pose a considerable risk to global food security. Typically plant pathogens are controlled through the use of chemical agents... -
The Kinetics of Ethanol Adsorption into Cholesterol Rich Bilayers
In a recent experiment carried out on SURF we have shown that on addition of ethanol to a DPPC model membrane, the anaesthetic initially diffuses to the bilayer surface followed... -
Temperature dependence of spin dynamics near quantum criticality in an Ising ...
This proposal is part of our research programme to explore the interplay of thermal and quantum fluctuations near zero-temperature quantum phase transitions. Here we apply for a... -
Quantum spin excitations of Cr-jarosite
Within the field of condensed matter physics, the study of frustrated antiferromagnets is at the forefront of current research. In frustrated antiferromagnets, the geometry of... -
A model of the bacterial outer membrane containing both Outer Membrane Protei...
We have recently improved the stability and coverage of free standing bilayers (FSB) by the use of a supporting thiolipid layer on gold. The system has been investigated on... -
Structure of a cationic polyelectrolyte adsorbed at an oppositely charged sur...
Adsorption of a charged polyelectrolyte onto an oppositely charged substrate is important for the understanding of many natural molecular events as well as for the development... -
Superconductivity induced changes in the ferromangetic order of Y(1-x)PrxBa2C...
By polarized neutron reflectometry we want to investigate the magnetic field profile in Y(1-x)PrxBa2Cu3O7/La(2/3)Ca(1/3)MnO3 high-Tc superconductor/ferromagnet superlattices. In... -
Effect of method of preparation on the composition of complex monolayers
In the present proposal neutron reflectivity will be used in combination with contrast variation to detect changes in the presence (and size) of microdomains in monolayer films... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also... -
Structure of a cationic polyelectrolyte adsorbed at an oppositely charged sur...
Adsorption of a charged polyelectrolyte onto an oppositely charged substrate is important for the understanding of many natural molecular events as well as for the development... -
Magnetic study of the new skyrmion-carrying material CoZnMn
Nanoscale magnetic skyrmions are swirl-like magnetisation entities that satisfy topological quantisation conditions. They can therefore not be easily unwound into another... -
Co-adsorption of monoclonal antibodies and non-ionic surfactants at the air/l...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show... -
Understanding the molecular origin of cononsolvency
The term cononsolvency has been used to describe a situation in which a polymer is less soluble in a mixture of two cosolvents than it is in either one of the pure solvents. If... -
Magnetic hysteresis loops in off-specular scattering
Reflectometry is a technique that is capable of vector magnetometry. By selecting the appropriate valves of Q we could access the different forms of magnetic disorder, either... -
Modes of protein adsorption at polyethylene oxide brushes of various polymer ...
We wish to understand the mechanism to which polymer brushes such as PEO resist the adsorption of protein and thus offer biocompatibility for various surface applications.... -
Characterising the membrane binding interaction of plant annexin Gh1
Annexins are a ubiquitous group of membrane associated proteins found in animals, plants and fungi. They are linked to wide range of functions including phospholipid... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the...